top of page

 

​

​

​

​

​

23.  Steven Ewell, Hannah Burton, Bereket Mochona*; In-Silico Screening of 1,3,4-Thiadiazole Derivatives as Inhibitors of Vascular Endothelial Growth

Factor - 2 (VEGFR-2). Curr. Issues Mol. Biol. 2024, 46(10), 11220-11235; https://doi.org/10.3390/cimb46100666.

​

22.  Bereket Mochona*, K. K. Redda, I. A. Offringa, J. Allen, J. D. Carpten, M. C. Stern, R. R. Reams, D. J. Wilkie; Mentoring Minority Cancer

Researchers of Tomorrow: Comparing the Face-to-Face, Virtual, and Hybrid Training Methods of CaRE2 Undergraduate Cancer Research Training.

Journal of Cancer Education (2024) 1.  DOI: 10.1007/s13187-024-02426-9

​

21. Reams, R.R., Odedina, F.T., Carpten, J.D., Redda, K., Stern, M. C., J. L., J. Hensel, B., Aberu, A., Adams, A., Agyare, E., Ali, J, Allen, J. M., Alo, R.,

Baezconde-Garbanati, L., Brant, J., Brown., C.P., Buxbaum, S.G., Cohen., P., Mochona, B., & Wilkie, D. J, Florida-California Cancer Research,

Education and Engagement (CaRE2) Health Equity Center: Structure and Initial Outcomes. Cancer Control (August 2023).  DOI: 10.1177/1073274823119   

​

20. Getinet Adinew, Samia Messeha, Equar Taka, Bereket Mochona, Kinfe Redda, Karam Soliman. Thymoquinone Inhibition of the Inflammatory and

Metastatic Effects of TNF-alpha Induced Chemokines in Triple Negative Breast Cancer Cells. International Journal of Molecular Sciences (June 2023)

doi.org/10.3390/ijms24129878   

​

19. Rajesh Thapa, Rafael Flores, Kwan H. Cheng, Bereket Mochona, and Donald Sikazwe. Design and Synthesis of New Acyl Urea Analogs as

Potential sigma 1 Receptor Selective Ligands. Molecules (2023) 28, 2319, 1-13. doi.org/10.3390/molecules28052319  

 

18. Getinet Adinew, Equar Taka, Bereket Mochona, Ramesh B. Badisa, Elizabeth Mazzio;Rashid Elhag, Karam F A Soliman. Therapeutic

Potential of Thymoquinone in TNBC Prevention and Progression Through the Modulation of the Tumor Microenvironment. Nutrients,

 14(79), (2022). https://doi.org/10.3390/nu14010079

 

17.   Clement G. Yedjou, Solange Tchounwou, Richard Alo, Rashid Elhag, Bekeret Mochona, and Lekan Latinwo. Application of Machine Learning

Algorithms in Breast Cancer Diagnosis and Classification. International Journal of Science Academic Research, 2(10), 3081-3086, (2021).

​

16. Bereket Mochona, D. Lyon, I. A. Offring, K. K. Redda, R. R. Reams, F. Odedina, D. J. Wilkie, M. C. Stern, J. D. Carpten; Developing a Novel

Framework for an Undergraduate Cancer Research Education and Engagement Program for Underrepresented Minority Students:

the Florida-California CaRE2 Research Education Core (REC) Training Program. Journal of Cancer Education (2020), https://doi.org/10.1007/s13187-020-01762-w

     

15.  Folakemi T. Odedina, L. S. Behar-Horenstein, P. Faith,  E. Kaninjing, J. Nguyen, R.R. Reams, B. Mochona, A. Ezeani, D.E. Lyon.; Improving

Representation of Underrepresented Minority (URM) Students in Oncology Biomedical Research Workforce: Outcome Evaluation from the ReTOOL

Program. Journal of  Cancer Education (2020). https://doi.org/10.1007/s13187-018-1344-6  

                                                                                                                                                                                                                

14. Folakemi T. Odedina, R.R. Reams, E. Kaninjing, J. Nguyen, B. Mochona, D.E. Lyon, L.S. Behar-Horenstein.; Increasing the Representation of

Minority Students in the Biomedical Workforce: the ReTOOL Program. Journal of  Cancer Education (2018). https://doi.org/10.1007/s13187-018-1344-6  

                                                                                                                                                                  

13. Rukhsar Banu, Jason Gerding, Cynthia Franklin, Donald Sikazwe, William Horton, Marianna Török, Julian Davis, Kwan H. Cheng, Muziya Nakazwe

and Bereket Mochona. 4,5-Dimethoxy-2-nitrobenzohydrazides and 1-(1-Benzylpiperidin-4-yl)ethan-1-ones as Potential Antioxidant/Cholinergic

Endowed Small Molecule Leads.  Sci. Pharm. 86, 2 (2018).

                                                                  

12. Suresh Eyunni, Madhavi Gangapuram, Bereket Mochona, Nelly Mateeva and Kinfe Redda. Synthesis and Biological Evaluations of Ring Substituted

Tetrahydroisoquinolines (THIQs) as Anti-Breast Cancer Agents. J. Cancer Sc. & Therapy; 9(7), 528-540, (2017).

​

11. Nelly Mateeva, Edikan Archibong and Bereket Mochona. Analysis of Dioxins and Dioxin-like Compounds in Food. Nova Scientific Publisher,

Chapter 1, PP. 1-32, (2017).

   

10. Bereket Mochona, Xin Qi, Suresh Euynni, Donald Sikazwi, Nelly Mateeva and Karam K. Solima. Design and Evaluation of Novel Oxidazole Derivatives

as Potential Prostate Cancer Agents. Bio. Org. Med. Chem. Lett. 26, 2847 – 2851, (2016).    

                                                      

9. Rafia Rahman, Muhammad A. Hanif, Zahid Mushtaq, Bereket Mochona and Xin Qi. Biosynthetic Factories of Essential Oils: The Aromatic Plants.

Natural Products Chemistry & Research, 4(4): 227 (2016)    

​

8. Bereket Mochona, Timothy Jackson, DeCoria McCauley, Elizabeth Mazzio, and Kinfe Redda. Synthesis and Cytotoxic Evaluations of Pyrrole

Hetarylazoles containing Benzimidazole/pyrazolones/1,3,4-oxadiazole Motifs. Journal of Heterocyclic Chemistry, 53, 1871 (2016).                                                                                                                                                                                                                      

 

7. Archibong, E., Foster, A., Caldwell, K., Lita, A., Mochona, B., Mateeva, N., “Synthesis, characterization, and electrospinning of novel polyaniline -

peptide polymers.” Applied Materials Today. 4, 78-82, (2016).    

                                                                                                         

6. Bereket Mochona, Elizabeth Mazzio, Madhavi Gangapurum, Nelly Mateeva and KinfeRedda. Synthesis of Some Benzimidazole Derivatives Bearing

1,3,4-Oxadiazole Moiety. Chem. Science Trans. 4(2), 534-540, (2015) 

   

5. Mateeva, N.N., Delab, S. D., Archibong, E. E., Tasheva, D., Mochona, B., Gangapuram, M., Redda., "Dansyl Substituted Aza Crown Ethers:

Complexation with Alkali, Alkaline Earth Metal Ions, and Ammonium," Intern. J. Chem., 3(1), 10-17, (2011).      

                               

4. B. Mochona, L. Le, M. Gangapuram, N. Mateeva, T. Ardley and K. Redda. Synthesis of 2-(N-Benzylpyrrolyl)-benzimidazoles using Polyphosphoric

Acid Prompted Cyclocondensation. Journal of Heterocyclic Chemistry (2010).                                                                

 

3. N. N. Mateeva, S. D. Deiab, E. E. Archibong, M. Jackson, B. Mochona, M. Gangapuram, K. K. Redda. Synthesis and Complexation Properties of

Novel N-(4-amino-7-nitrobenzaoxa-1,3-diazole) - Substituted Aza Crown Ethers. Journal of Inclusion Chemistry (2010).  

 

2. B. Mochona and K. K. Redda.  Synthesis of N-Benzoyl-1,2,3,6-Tetrahydropyridine Derivatives as Potential Anti-inflammatory Agents. J. Heterocyclic

Chem. 1383-1387 (2007).                                                                                                                                          

1. B. Mochona, T. L. Wilson, and K. K. Redda. Synthesis and Anti-inflammatory Activities of Analogues of N- Benzoylamino- 1,2,3,6- tetrahydropyridines

. Drugs under Experimental and Clinical Research (2003)                                                

 

Selected Conference Presentations                                                              

​

  • Undergraduate Research Symposium Presentation: "Design and Synthesis of Novel Oxadiazole Derivatives as Androgen Receptor Inhibitors," Micah Williams, Steven Ewell, Bereket Mochona. Tallahassee, Florida, April 2024.

​

  • Undergraduate Research Symposium Presentation: "Dual Kinase Inhibitors: Structure-activity Relationships of Piplartine Analogs as c-Met and Tyrosine Kinase Inhibitors," Hannah Burton, Steven Ewell, Bereket Mochona. Tallahassee, Florida, April 2024.

​

  • Undergraduate Research Symposium Presentation: "In Silico Identification of Novel Quinolone Derivatives as Tyrosine Kinase Inhibitors for Triple Negative Breast Cancer," Sydnee Fo, Steven Ewell, Bereket Mochona. Tallahassee, Florida, April 2024.

​

  • CADD Research Presentation: "In Silico Identification of Oxadiazole Derivatives as VEGFR-2 Inhibitors for Triple Negative Breast Cancer Therapy," Sydnee Fo, Steven Ewell, Bereket Mochona.  Tallahassee, Florida, February 2024.

​

  • "AI-Integrated Computer Aided Drug Design: A Pathway to Workforce Diversity in Oncology."  Steven Ewell and Bereket Mochona. Presented Webinar at Florida-California Cancer Research, Education and Engagement Health Equity Center, February 2024

​

  • “In-Silico Identification of Thiazole as Triple-Negative Breast Cancer Therapeutic Agents with Vascular Endothelial Growth Factor Receptor-2 (VEGFR-2) Inhibitory Effect” Steven Ewell, Getinet Mequanint, Donald Sikazwe, Kinfe Redda, Bereket Mochona. Presented Poster at 2023 Annual Biomedical Research Conference for Minoritized Scientists (ABRCMS), Phoenix, Arizona, November 2023

​

  • “In-Silico Identification of Oxazole Carboxamides as Cancer Therapeutic Agents with c-Mesenchymal Epithelial Transition (c-MET) Inhibitory Effect” Steven Ewell, Getinet Mequanint, Donald Sikazwe, Kinfe Redda, Bereket Mochona. 2023 16th AACR Conference on The Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, Orlando, Florida, September-October 2023

​

  • “In-Silico Identification of Thiazole Carboxamides as Cancer Therapeutic Agents with Vascular Endothelial Growth Factor Receptor-2 (VEGFR-2) Inhibitory Effect” Steven Ewell, Getinet Mequanint, Donald Sikazwe, Kinfe Redda, Bereket Mochona. Fall 2023 American Chemical Society (ACS), San Fransico, California, August 2023

​

  • “In Silico Identification of 1,3,4-Oxadiazole Hybrids as novel Discoidin Domain Receptor-1 (DDR-1) Inhibitors with Potential Triple-Negative Breast Cancer Agent” Steven Ewell, Linda Williams, Clement Yadjou, Suresh Eyunni and Bereket Mochona. American Association for Cancer Research (AACR) Undergraduate Student Caucus and Poster Competition, Orlando, Florida, April 2023

​

  • In Silico Identification of 1,3,4-Oxadiazole Hybrids as novel Discoidin Domain Receptor-1 (DDR-1) Inhibitors with Potential Anticancer Agent” Steven Ewell, Linda Williams, Clement Yadjou, Suresh Eyunni and Bereket Mochona. Awarded 1st Place at the Emerging Researchers National (ERN) Conference, Washington, D.C., February 2023

​

  • Design and synthesis of tetrahydropyridine analogs as selective COX-2 inhibitors and anti-breast cancer agents Shasline Gedeon; Madhavi Gangapuram; Suresh Eyunni; Bereket Mochona; Tiffany Ardley; Kinfe Ken ReddaDesign, Synthesis & Spectral Studies of Piplartine Analogues Carrying Pyrazole, AACR (2022), (Abstract PO-103)

​

  • Pyrrole & 1,3,4-Oxadiazole Moieties as Anticancer Agents with Anti-inflammatory Effects Chukwuemelie E. Okwo, Xin Qi, Donald Sikazwi Elizabeth Mazzio and Bereket Mochona. Annual Biomedical Research Conference for Minority Students, November 13 -16, 2019,  Anaheim, California (abstract #  B-19)

​

  • Piplartine Analogues Bearing 1,3,4-oxadiazoles as Potential Anticancer Agents. Jessi Noel and Bereket Mochona. Annual Biomedical Research Conference for Minority Students, November 13 -16, 2019, Anaheim, California (abstract #  D-137).                      

​

  • Florida-California Cancer Health Disparity Research, Education & Engagement (CaRE2) Center: Research Education Overview and Preliminary Results. Bereket Mochona, Debra Lyon, Ite A. Offringa, Kinfe K. Redda, R. Renee Reams4, Folakemi Odedina5, Diana J. Wilkie, John D. Carpten and Mariana C. Stern. 12th American Association for Cancer Research Conference on the Science of Cancer Health Disparities, September 20-23, 2019, San Francisco, CA (abstract #D076).      

​

  • Tracking of Undergraduate Research Trainees for Continous Improvement of the ReTOOL Program. Parisa Fathi, Folakemi Odedina, Bereket Mochona, R. Renee Reams, Jennifer Nguyen, Nissa Askins, Debra Lyon, Ernest Kaninjing, Merr Jennifer. 12th American Association for Cancer Research Conference on the Science of Cancer Health Disparities, September 20-23, 2019, San Francisco, CA (abstract #D035).             

​

  • Anti-inflammatory properties of synthetic chalcones and ∆1-pyrroline-5-carbonitriles. Aikens, Cecilia; Mazzio, Elizabeth; Mihaylova, Vessela; Tasheva, Donka; Mochona, Bereket; Redda, Kinfe; Mateeva, Nelly N. Source: Abstracts of Papers, 255th ACS National Meeting & Exposition, New Orleans, LA, United States, March 18-22, 2018, Pages: MEDI-163,            

​

  • Inhibition of breast cancer cell growth and proliferation by novel synthetic ∆1-pyrroline-5-carbonitriles and flavonoids. Aikens, Cecilia; Mihaylova, Vessela; Tasheva, Donka; Mazzio, Elizabeth; Mochona, Bereket; Redda, Kinfe; Mateeva, Nelly N. 255th ACS National Meeting & Exposition, New Orleans, LA, United States, March 18-22, 2018, Pages: MEDI-164.      

​

  • Ring Substituted Tetrahydroisoquinolines As Anti-Breast Cancer Agents . SVK EYUNNI; M Gangapuram; KK Redda; B Mochona; N Mateeva . Annual RCMI Conferenc, Washington, D.C. (Oct 28-Nov 1, 2017)          

​

  • Odedina, FT Reams, RR, Daaka, Y,; Nguyen, J; Suther, S; Markham, MJ; Mochona, B; George, T; Okunieff, P; Moore, T; Harris, C, Soliman, K . “Florida Minority Cancer Research and Training (MiCaRT) Center. NCI-Center to Reduce Cancer Health Desparities, 2016 Partnerships to Advance Cancer Health Equity Investigators Meeting, Rockville, MD, June 13-14, 2016.   

​

  • Bereket Mochona, Suresh Eyunni, Elizabeth Mazzio and KinfeRedda. Synthesis, Cytotoxic Activities and Cell Cycle Arrest Profiles of Benzimidazole - 1,3,4-Oxadiazole Conjugates. 251st ACS National Conference. San Diego, Ca, March, 2016.                     

​

  • Bereket Mochona, Suresh Eynni and Elizabeth Mazzio. Search for Anti-Cancer Agents that Target Two or Three Proteins Simultaneously: Inhibition of Anti-apoptotic BCL-2 Family Proteins and Androgen Receptor Expressions. The 3rdAnnual Florida Health Equity Research lnstitute (HERI) Summit, Tampa, Florida, Feb. 5-6, 2016.    

​

  • Bereket Mochona, Elizabeth Mazzio, Nelly Mateeva and KinfeRedda. “Synthesis, Cytotoxcity and Cell Cycle Arrest Profile of Benzimidazole-1,3,4-Oxadiazole Conjugates.” 251st ACS National Meeting and Exposition, San Diego, CA, March 13-17, 2016.

​

​

  • Victoria Barnes, Xin Qi, Elizabeth Mazzo, Suresh Eyunni and Bereket Mochona. “Synthesis and In-vitro Anticancer Evaluations of 1,3,4-Oxadiazolyl- Benzimidazole Conjugates”. Annual Biomedical Research Conference for Minority Students. Seattle, Washington, Nov. 2015.  

​

  • Timothy Jackson, E. Mazzio, K. K. Redda and Bereket Mochona.Molecular Properties Prediction, Synthesis and In-Vitro Anticancer Evaluations of Some Benzenesulfonylhydrazide Schiff Base Analogues. Florida Annual Meeting and Exposition (FAME), Innisbrook Resort and Golf Club, Florida, May, 2015.

​

  • Nelly Mateeva, DonkaTasheva, Krista Cabret, Bereket Mochona,KinfeRedda “Synthesis and biological evaluation of novel flavonoid derivatives as anticancer agents”. 248th ACS National Meeting and Exposition, San Francisco, CA, August 10-14, 2014

​

  • Bereket Mochona, Elizabeth Mazzo, Larry Russell, Nelly Mateeva, Kinfe K. Redda. ” Synthesis, anticancer, and antioxidant activities of some pyrrolyl-1-3,4-oxadiazole and pyrrolyl-4-aminoantpyrine Schiff base analogs,”  248th ACS National Meeting and Exposition, San Francisco, CA, August 10-14, 2014. 

​

  • Bereket Mochona,E. Mazzo, D. McCauley and K. Redda. “Synthesis and Anticancer Evaluation of Pyrrolyl-1,3,4-Oxadiazole Conjugates Characterized by Schiff Base and Amide Linkage”  247th American Chemical Society National Meeting & Exposition, Dallas, TX. March 16-20, 2014.

​

  • Shade Ahmed and Bereket Mochona. “Synthesis of 1,3,4-Oxadiazole-Pyrrole Hybrids for Evaluation as Anti-Cancer Agents. Florida-Georgia Louis Stokes Alliance for Minority Participation (FGLSAMP) Expo 2014, Jacksonville, FL, Feburary 13-15, 2014.

​

  • Shade Ahmed, Kinfe Redda and Bereket Mochona.“Synthesis of 1,3,4-Oxadiazole-Pyrrole Hybrids for Evaluation as Anti-Cancer Agents. Annual Biomedical Research Conference for Minority Students (ABRCMS) , Nashville, TN, November 13-16, 2013.

​

  • Bereket Mochona, Elizabeth Mazzio, Nelly Mateeva and KinfeRedda. “Pyrolyloxadiazoles : Synthesis and Preliminary Pharmacological Evaluations as Anticancer Agents”  89thFlorida Annual Meeting and Exposition (FAME), Innisbrook Resort and Golf Club, Florida, May, 2013.  

​

  • Kinfe Ken Redda, Madhavi Gangapuram, Mohammad A. Ghaffari, Suresh Eyunni, Nelly Mateeva, Bereket Mochona.   “Synthesis of heterocyclic compounds as anticancer agents.” 104thAACR Annual Meeting 2013;Washington, DC, Apr 6-10, 2013

​

  • Madhavi Gangapuram,B. Mochona, Nelly Mateeva, Tiffany Ardley and Kinfe K. Redda,“synthesis of substituted N-(3-(1H-pyrrol-1yl)methyl-5,6-dihydropyridin-1(2H)-yl)benzamide/ benzene sulfonamide as anticancer agents, American Association for Cancer Research (AACR), 102th  AACR Annual Meeting, Orlando, FL, April 2 -6, 2011.

​

  • Nelly N. Mateeva, Edikan E. Archibong, Ling Wang1, Adrian Lita, B. Mochona, Kinfe K. Redda, “Extraction and Determination of TCDD and AROCHLORS.”  May 2011, FAME 2011    

​

  • Said Farah, Madhavi Gangapuram, Nelly Mateeva, B. Mochona, Tiffany Ardley and Kinfe Ken Redda, “Synthesis of substituted N-(4-(6-methyl-1H-benzo[d]imidazol-2-yl)-5,6-dihydropyridin-1(2H)-yl) benzamide / benzensulfonamide as anticancer agents” (Abstract Number: 11-A-1749-AACR)presented at the 2011 American Association for Cancer Research (AACR), 102th  AACR Annual Meeting, Orlando, FL, April 2 -6, 2011.    

​

  • B. Mochona,  Adonis McQueen, Nelly N. Mateeva, Kinfe K. Redda, “Synthesis of 2-(N-benzoylpyrolyl)-benzimidazoles using polyphosphoric acid prompted cyclocondensation”, (Abstract #240) presented during the  86th, 2010 American Chemical Society (ACS) - Florida Annual Meeting and Exposition (FAME), Innisbrook Resort and Golf Club, Florida, May, 2010.   

​

  • Nelly N. Mateeva, Shihab D. Deiab, Edikan E. Archibong, B. Mochona,Madhavi Gangapram, Kinfe K. Redda, “N-(4-amino-7-nitrobenzaoxa-1,3-diazole) substituted aza crown ethers: complexation with alkali, alkaline earth metal ions and ammonium”, I (Abstract #52) presented during the  86th, 2010 American Chemical Society (ACS) - Florida Annual Meeting and Exposition (FAME), Innisbrook Resort and Golf Club, Florida, May 13-15, 2010.

​

  • Nelly N. Mateeva, Shihab D. Deiab, Edikan E. Archibong, B. Mochona,MadhaviGangapram, Kinfe K. Redda, “N-(4-amino-7-nitrobenzaoxa-1,3-diazole) substituted aza crown ethers: complexation with alkali, alkaline earth metal ions and ammonium””, II (Abstract #130) presented during the  86th, 2010 American Chemical Society (ACS) - Florida Annual Meeting and Exposition (FAME), Innisbrook Resort and Golf Club, Florida, May 13-15, 2010.  

​

  • Marsha Boatwright,Edikan E. Archibong, Shihab D. Deiab, B. Mochona, Nelly N. Mateeva, Kinfe K. Redda, “Determination of amino acids using Fluoro labeled crown ethers and cyclodoxterins”,  (Abstract #176) presented during the  86th, 2010 American Chemical Society (ACS) - Florida Annual Meeting and Exposition (FAME), Innisbrook Resort and Golf Club, Florida, May 13-15, 2010.  

 

bottom of page